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On this page: • • • • • • • • What is EPI Suite ™? The EPI (Estimation Programs Interface) Suite™ is a Windows®-based suite of physical/chemical property and environmental fate estimation programs developed by EPA’s and Syracuse Research Corp. EPI Suite™ uses a single input to run the following estimation programs: KOWWIN™, AOPWIN™, HENRYWIN™, MPBPWIN™, BIOWIN™, BioHCwin, KOCWIN™, WSKOWWIN™, WATERNT™, BCFBAF™, HYDROWIN™, KOAWIN and AEROWIN™, and the fate models WVOLWIN™, STPWIN™ and LEV3EPI™. ECOSAR™, which estimates ecotoxicity, is also included in EPI Suite™. EPI Suite™ is a screening-level tool and should not be used if acceptable measured values are available. A clear understanding of the estimation methods and their appropriate application is very important.

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Click on the Help tab in EPI Suite™ for detailed information on the methods and models in it. How are EPI Suite™ estimates used? EPI Suite™ provides users with estimates of physical/chemical and environmental fate properties. Before using EPI Suite™, users should first determine whether any suitable data are available from the literature (e.g., Merck Index, Beilstein). This is facilitated by a database of >40,000 chemicals (called PHYSPROP©) that is included in the EPI Suite™ software.

Microsoft Office shared tools are software components that are (or were) included in all. The program is available as an OLE application object in Visual Basic. WordArt is available in 30 different preset styles in Microsoft Word, however, it is. Its abilities include symbolic integration, 3D plotting and solving differential equations. The Maxima source code can be compiled on many systems, including Windows, Linux, and MacOS X. 5.40.0: May 30, 2017. GPL and should accompany other modifications, enhancements or derivative works of your program.

Dermwin™, a program that estimates the dermal permeability coefficient Kp, and is included in EPI Suite™. ECOSAR™ is a program that predicts aquatic toxicity and is included in EPI Suite™. ECOSAR™ can also be downloaded as a separate program from the ECOSAR home page. Individual models in EPI Suite™ • KOWWIN™: Estimates the log octanol-water partition coefficient, log KOW, of chemicals using an atom/fragment contribution method. • AOPWIN™: Estimates the gas-phase reaction rate for the reaction between the most prevalent atmospheric oxidant, hydroxyl radicals, and a chemical. Gas-phase ozone radical reaction rates are also estimated for olefins and acetylenes.

In addition, AOPWIN™ informs the user if nitrate radical reaction will be important. Atmospheric half-lives for each chemical are automatically calculated using assumed average hydroxyl radical and ozone concentrations. • HENRYWIN™: Calculates the Henry’s Law constant (air/water partition coefficient) using both the group contribution and the bond contribution methods. • MPBPWIN™: Melting point, boiling point, and vapor pressure of organic chemicals are estimated using a combination of techniques. Included is the subcooled liquid vapor pressure, which is the vapor pressure a solid would have if it were liquid at room temperature.

It is important in fate modeling. • BIOWIN™: Estimates aerobic and anaerobic biodegradability of organic chemicals using 7 different models. Two of these are the original Biodegradation Probability Program (BPP™). The seventh and newest model estimates anaerobic biodegradation potential. • BioHCwin: Estimates biodegradation half-life for compounds containing only carbon and hydrogen (i.e. • KOCWIN™: Formerly called PCKOCWIN™, this program estimates the organic carbon-normalized sorption coefficient for soil and sediment; i.e. KOC is estimated using two different models: the Sabljic molecular connectivity method with improved correction factors; and the traditional method based on log KOW.